Wegovy is now the first weight loss medication to also be approved to help prevent life-threatening cardiovascular events in adults with CVD and either obesity or overweight, John Sharretts, MD, director of the division of diabetes, lipid disorders and obesity in the FDAs Center for Drug Evaluation and Research, said in the statement
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However, in the post-surgical context, distinguishing between medication side effects and surgical complications can be challenging
L-F001 and dimethyl fumarate (DMF) exemplify this paradigm, simultaneously targeting oxidative stress (including ferroptosis), inflammation (e.g., via NF-B), and in DMFs case, even promoting astrocytic health (Peng, 2022