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Summary: Combining retatrutide and sermorelin in a stack has no clinical evidence base, and both compounds are unlicensed in the UK, making this combination potentially dangerous and legally problematic

In clinical trials, patients who took Semaglutide lost an average of 10-15% of their body weight within just 12 months, with some patients losing as much as 20% of their initial body weight

However, individuals with diabetes and higher BMIs may find these medications particularly beneficial if weight loss is a primary goal in their diabetes treatment plan

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