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The sustained action of glucagon causes hyperglycemia and glucose mediated inhibition of glucagon secretion is impaired in patients with T2DM
doi:10.1186/s12970-017-0173-z Buford TW, Kreider RB, Stout JR, Greenwood M, Campbell B, Spano M, et al
Common contributors include sleep disorders, chronic stress, hormonal imbalances (particularly thyroid dysfunction), nutritional deficiencies (such as vitamin B12 or iron), autoimmune conditions (like multiple sclerosis or lupus), medications, and metabolic disorders including diabetes
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