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In support, Li et al
The foundational research here traces back to Loren Pickart, whose decades of work culminated in a widely cited 2018 review in the International Journal of Molecular Sciences documenting that GHK-Cu modulates the activity of thousands of human genes tied to tissue remodeling, antioxidant defense, and inflammatory regulation
Supports the statement that glutathione reductase converts GSSG back to reduced GSH using NADPH
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