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Furthermore, oxidative stress is a critical activator of inflammasomes, particularly the NLRP3 inflammasome (Jomova et al., 2023), leading to the release of potent pro-inflammatory cytokines that drive sterile inflammation and contribute significantly to tissue damage (Zhang H
The aim of the present study was to compare the efficacy of niosome with topical glutathione gel 2% in the treatment of melasma versus topical glutathione gel 2% alone
This transport process includes several steps ('carnitine shuttle'), which are described above for VPA [34, 35]
For example, the combination of metformin with combined oral contraceptives has shown enhanced benefits on hormonal and metabolic parameters compared to either treatment alone
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