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Targeting the hepcidin-ferroportin pathway by inhibiting the bone morphogenic protein BMP6, which stimulates hepcidin expression in the liver or the iron exporter ferroportin via the monoclonal antibodies, LY3113593 and LY2928057, has not been further investigated beyond a phase 1 study (177)

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Maiseyeu A, Di L, Ravodina A, Barajas-Espinosa A, Sakamoto A, Chaplin A, et al

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