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The compound long half-life means effects persist for several weeks after the last administration, which must be factored into any pause or discontinuation decision
You have never had your bone status checked You are in one of these higherrisk groups and have never had a DEXA scan or a real conversation about bone risk You plan to start or stay on tirzepatide for the long haul without any baseline bone data to compare against If you see yourself in several of these buckets, you need a bonefirst plan on tirzepatide: baseline DEXA, targeted labs, and a clear musclepreserving strategy baked into your protocol from day one
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With the right plan, you can make steady, sustainable progress toward your weight-loss goals, without combining medications that were never meant to be taken together
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