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The Endocrine System comprises a series of glands that release different hormones that target specific things in the body and has many significant jobs, including regulating your metabolism and helping to maintain your blood pressure and heart rate
Generally I refer to both of these drugs as incretin medicines because they work to enhance natural gut hormones called incretins (GLP-1 and GIP)
nuclear receptors peroxisome proliferator-activated receptor (PPAR), 9 and thyroid hormone receptor beta (THRb) 10 as well as antidiabetic-peptide receptors GLP-1 receptor (GLP1R), 11 glucagon receptor (GCGR) 12 and GIP receptor (GIPR), 13 which alter glucose and lipid metabolism
Other obvious limitations of this Polish study (132) are the lack of details on the degree of hypothyroidism (overt, subclinical, either), the magnitude of change in serum levels of TSH, and having neglected to obtain information on changes in serum thyroid autoantibodies
