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It has been "well-established" that autoimmune patients who also have obesity "fare worse" than those who are at a healthy weight, according to Dr

In contrast, no benefits on the rate of decline in glomerular filtration rate have been seen in trials of DPP-4 inhibitors, perhaps because the renal actions of DPP-4 inhibitors are primarily mediated by potentiation of SDF-1, not GLP-1