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Mansour A, Mousa M, Abdelmannan D et al (2023) Microvascular and macrovascular complications of type 2 diabetes mellitus: exome wide association analyses

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GLP-1 Preclinical Study Design and Methods To evaluate systemic toxicity and toxicokinetic characteristics of the GLP-1 RA test article and potential reversibility of any findings, we designed an IND-enabling study that included: a robust dosing schedule of daily oral administration for 28 days