tirzepatide average monthly weight loss weight-loss study shows promising results How much weight did you

Participants were asked to complete the questionnaire according to their perceptions of their daily practice environment within their specialty, and not reflecting their own personal clinical practice

In the STEP (Semaglutide Treatment Effect in People with obesity) trials, participants receiving semaglutide achieved an average weight loss of 15-20% over the course of 68 weeks

This biological recalibration helps prevent rapid weight rebound when treatment continues long-term

Retatrutide produced 24.2% average weight loss at 48 weeks through triple receptor agonism (GIP/GLP-1/Glucagon), while Survodutide achieved 14.9-18.7% weight loss at 46 weeks through dual receptor agonism (GLP-1/Glucagon)