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Current AD research focuses on understanding pathology by targeting several mechanisms, such as abnormal tau protein metabolism, -amyloid, inflammatory response, and cholinergic and free radical damage, aiming to develop successful treatments that are capable of stopping or modifying the course of AD (Tamagno et al., 2021)

A 2.38-fold increase in hair count ratio versus 1.21 for placebo represents a clinically meaningful difference that patients would notice visually

7 Clinical note: These mechanisms are derived from preclinical models

Which approach suits a study depends entirely on the research design single-compound vials are also available individually