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Tissue perfusion and sexual function pathways A case report of female anorgasmia and hypoarousal temporally related to GLP-1 agonist use (including semaglutide after a switch from liraglutide) proposed mechanisms including smooth-muscle vasoconstriction with reduced genital blood flow and central neurotransmitter pathway effects (hypothalamic signalling)
If stomach discomfort shows up after a dose increase, it may ease as the body gets used to the new dose
Acta Biomater 113:4262
Sende is a double board-certified physician specializing in obesity medicine and internal medicine, practicing in Miami, Florida
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