Neuronale Zeroidlipofuszinose 6 (NCL-6) Einzelanalyse Affecteddogs have abnormal platelet function

Affecteddogs have abnormal platelet function because they are not able to stick together properly and therefore cannot form a clot

aber ältere Tiere leiden unter Lethargie und episodischer Hypoglykämie mit Kollaps

Mutation: F8 gene

Because production of eumelanin is disabled

Neuronale Zeroidlipofuszinose 6 (NCL-6) Einzelanalyse Affecteddogs have abnormal platelet functionNeuronal ceroid lipofuscinoses (NCLs) are a group of heritable diseases characterized by progressive neuronal degeneration and the accumulation of autofluorescent cytoplasmic inclusions in the brain, retina and other tissues. Clinical symptoms and progress of the disease include increased rates of irritability, with the possibility of outbursts of aggression, hallucinations, hyperactivity and seizures. Most animals lose their ability to coordinate